Nick Willett

Affiliated Faculty

Current Research

Musculoskeletal diseases and injuries are a major burden on society, representing one of the most common causes of pain and impaired function worldwide. This burden is largely due to inadequate diagnostic, preventative and interventional techniques for conditions such as osteoarthritis and multi-tissue limb reconstruction. A limiting factor in addressing these challenges is that the musculoskeletal system is often studied and treated as independent tissues rather than functionally integrated units. This narrow focus has restricted the understanding of key mediators, both mechanical and molecular, which act during musculoskeletal disease and regeneration. The overall goal of my research is to develop a systems integration approach to musculoskeletal disease and regenerative engineering. I am currently working on two projects: one related to bone-muscle interactions during tissue regeneration and the other related to quantitative 3D characterization of cartilage degeneration in rat osteoarthritis models. Details on the composite injury project can be found in a recent publication: http://online.liebertpub.com/doi/full/10.1089/ten.tec.2012.0290n/a
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Additional Info

Emory University